Novel compound AC102 restores hearing in preclinical models of sudden hearing loss
The effect of AC102 on OHC survival after noise exposure in vivo. (A) Schematic of OHCs and IHCs within the ...
The effect of AC102 on OHC survival after noise exposure in vivo. (A) Schematic of OHCs and IHCs within the ...
PBA treatment reduces PERK activity and increases XBP1s in the hippocampus of APPNL-G-F knock-in (KI) mice. Confocal images of the ...
Prenatal transplantation of human PLC-mcoET3 results in increased FVIII activity levels in circulation for at least 3 years after treatment. ...
Credit: CC0 Public Domain A subtype of CD8 T cells, which are classically known to promote immune system responses, may ...
B-COBRA HA antigens for the vaccination and infection of pre-immune ferrets. Credit: Scientific Reports (2023). DOI: 10.1038/s41598-023-43003-2 Recent preclinical results ...
Credit: CC0 Public Domain It is an all-too-common fact that potential drugs can look extremely promising in preclinical laboratory testing ...
Graphical abstract. Credit: Molecular Therapy (2023). DOI: 10.1016/j.ymthe.2023.07.022 An experimental mRNA vaccine provides protection in preclinical animal models against infection ...
Graphical abstract. Credit: Molecular Therapy (2023). DOI: 10.1016/j.ymthe.2023.07.015 When Richard O'Neil, Ph.D., joined MUSC Hollings Cancer Center two years ago, ...
The City of Hope-developed small molecule AOH1996 targets a cancerous variant of the protein PCNA. In its mutated form, PCNA ...
Intermediate magnification micrograph of a low malignant potential (LMP) mucinous ovarian tumour. H&E stain. The micrograph shows: Simple mucinous epithelium ...